Doctrine of the Signatures, the theory of medicine that like cures like. Varieties of Hepatica (Liverwort) - 1,2,3 - and Geranium. The leaves of Hepatica were thought to resemble the liver, and were used to coole and strengthen that organ. According to Camerarius, Geraniums were a singular remedy against the Stone both in the reines (kidneys) and bladder. Woodcut from Paradisi in Sole Paradisus Terrestris by John Parkinson (London, 1629).