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Colon cancer, illustration. From left to right: in Stage 0 the cancer has not grown beyond the inner layer of the colon wall. In Stage1 the cancer has grown to the outer layer of the wall. In Stage 2 the tumor has grown through the wall but not spread to the lymph nodes. In Stage 3 the tumor has spread to the lymph nodes. In Stage 4 the cancer has spread to distant sites in the body.

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