Ren矇 Jules Dubos (February 20, 1901 - February 20, 1982) was a French-American microbilogist and winner of the Pulitzer Prize for his book "So Human An Animal". He is credited as an author of a maxim, "Think globally, act locally". He devoted most of his professional life to the empirical study of microbial diseases and to the analysis of the environmental and social factors that affect the welfare of humans. His pioneering research in isolating antibacterial substances from certain soil microorganisms led to the discovery of major antibiotics. He performed groundbreaking research and wrote extensively on a number of subjects, including tuberculosis, pneumonia, and the mechanisms of acquired immunity, natural susceptibility, and resistance to infection. In later years, He explored the interplay of environmental forces and the physical, mental and spiritual development of mankind. The main tenets of his humanistic philosophy were: global problems are conditioned by local circumstances and choices, social evolution enables us to rethink human actions and change direction to promote an ecologically balanced environment, the future is optimistic since human life and nature are resilient and we have become increasingly aware of the dangers inherent in natural forces and human activities, and we can benefit from our successes and apply the lessons learned to solving other contemporary environmental problems. He died in 1982 on his 81st birthday.