Symptoms of coronavirus infection, illustration. The main symptoms of an infection with the Sars-CoV-2 virus may vary, but most often include headache, rheumatic pains, fever and weakness. In most cases, a sore throat is present, as well the loss of the sense of taste and smell. In severe cases, people develop coughing, shortness of breath and the destruction of the alveoli, leading to pneumonia. Some people may have stomach trouble.